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The crosstalk between the caspase family and the cGAS‒STING signaling pathway
Yongai Xiong1 , Yan-Dong Tang2,3 , Chunfu Zheng2,4,*
1Key Laboratory of Basic Pharmacology of Guizhou Province and School of Pharmacy; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China
2Department of Immunology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China
3State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, China
4Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada
*Correspondence to:Chunfu Zheng , Email:zheng.alan@hotmail.com
J Mol Cell Biol, Volume 13, Issue 10, October 2021, 739-747,  https://doi.org/10.1093/jmcb/mjab071
Keyword: cGAS‒STING, caspases, innate immunity, signaling pathway

Edited by Jiarui Wu

Cytosolic nucleic acid sensors are critical for sensing nucleic acids and initiating innate immunity during microbial infections and/or cell